Rand兰德：2026年弥合数字与物理鸿沟：大语言模型智能体台式DNA获取能力评估报告（英文版）

This report describes eight frontier large language model (LLM) agents on their ability to design DNA segments, interact with a benchtop DNA synthesizer, and generate laboratory protocols. These are dual-use tasks, explored as potential technical bottlenecks to a malicious actor building a viral pathogen that could be weaponized. Performance varied among the models, but all tested LLMs designed biologically coherent DNA segments in some attempts.